Recent scientific approaches to aesthetics include evolutionary theories about the origin of art behavior, psychological investigations into human aesthetic experience and preferences, and neurophysiological explorations of the mechanisms underlying art experience. Critics of these approaches argue that they are ultimately irrelevant to a philosophical aesthetics because they cannot help us understand the distinctive conceptual basis and normativity of our art experience. This criticism may seem plausible given the piecemeal nature of these scientific approaches, but a more comprehensive naturalistic framework can (...) help us understand the conceptual basis and normativity of art. In particular, the ecology of art, an understanding of how individuals interact within particular environments, can help us understand the engineered art niches in which we create and experience art. Each niche is associated with a particular deme, or set of individuals that interact within that niche, and a set of cognitive, epistemic, and pedagogical technologies that form the conceptual basis of a niche-dependent normativity. This is to be contrasted with the niche-independent normativity revealed by many of the scientific approaches. This framework, and the conflicting streams of normativity it reveals, allows us to better understand conflicts in normativity and the implausibility of unequivocal and universal normative principles. (shrink)

Disagreement is common: even informed, intelligent, and generally reasonable people often come to different conclusions when confronted with what seems to be the same evidence. Can the competing conclusions be reasonable? If not, what can we reasonably think about the situation? This volume examines the epistemology of disagreement. Philosophical questions about disagreement arise in various areas, notably politics, ethics, aesthetics, and the philosophy of religion: but this will be the first book focusing on the general epistemic issues arising from informed (...) disagreement. Ten leading philosophers offer specially written essays which together will offer a starting-point for future work on this topic. (shrink)

It is proposed that our memory is made up of individual, unconnected Records, to each of which is attached a Heading. Retrieval of a Record can only be accomplished by addressing the attached Heading, the contents of which cannot itself be retrieved. Each Heading is made up of a mixture of content in more or less literal form and context, the latter including specification of environment and of internal states (e.g. drug states and mood). This view of memory allows an (...) easy account of a number of natural memory phenomena as well as a variety of laboratory findings such as the differences between recall and recognition. The theory further proposes that Headed Records can neither be deleted nor modified. Data apparently against such a hypothesis can be accounted for in terms of the retrieval process. (shrink)

Efforts by governments, firms, and patients to deliver pioneering drugs for critical health needs face a challenge of diminishing efficiency in developing those medicines. While multi-sectoral collaborations involving firms, researchers, patients, and policymakers are widely recognized as crucial for countering this decline, existing incentives to engage in drug development predominantly target drug manufacturers and thereby do little to stimulate collaborative innovation. In this mini review, we consider the unexplored potential within pharmaceutical regulations to create novel incentives to encourage a diverse (...) set of actors from the public and private spheres to engage in the kind of collaborative knowledge exchange requisite for fostering enhanced innovation in early drug development. (shrink)

Is the societal-level of analysis sufficient today to understand the values of those in the global workforce? Or are individual-level analyses more appropriate for assessing the influence of values on ethical behaviors across country workforces? Using multi-level analyses for a 48-society sample, we test the utility of both the societal-level and individual-level dimensions of collectivism and individualism values for predicting ethical behaviors of business professionals. Our values-based behavioral analysis indicates that values at the individual-level make a more significant contribution to (...) explaining variance in ethical behaviors than do values at the societal-level. Implicitly, our findings question the soundness of using societal-level values measures. Implications for international business research are discussed. (shrink)

This paper applies a virtue epistemology approach to using the Internet, as to improve our information-seeking behaviours. Virtue epistemology focusses on the cognitive character of agents and is less concerned with the nature of truth and epistemic justification as compared to traditional analytic epistemology. Due to this focus on cognitive character and agency, it is a fruitful but underexplored approach to using the Internet in an epistemically desirable way. Thus, the central question in this paper is: How to use the (...) Internet in an epistemically virtuous way? Using the work of Jason Baehr, it starts by outlining nine intellectual or epistemic virtues: curiosity, intellectual autonomy, intellectual humility, attentiveness, intellectual carefulness, intellectual thoroughness, open-mindedness, intellectual courage and intellectual tenacity. It then explores how we should deploy these virtues and avoid the corresponding vices when interacting with the Internet, particularly search engines. Whilst an epistemically virtuous use of the Internet will not guarantee that one will acquire true beliefs, understanding or even knowledge, it will strongly improve one’s information-seeking behaviours. The paper ends with arguing that teaching and assessing online intellectual virtues should be part of school and university curricula, perhaps embedded in critical thinking courses, or even better, as individual units. (shrink)

Most models of generational succession in sexually reproducing populations necessarily move back and forth between genic and genotypic spaces. We show that transitions between and within these spaces are usually hidden by unstated assumptions about processes in these spaces. We also examine a widely endorsed claim regarding the mathematical equivalence of kin-, group-, individual-, and allelic-selection models made by Lee Dugatkin and Kern Reeve. We show that the claimed mathematical equivalence of the models does not hold. *Received January 2007; revised (...) April 2008. †To contact the authors, please write to: Elisabeth Lloyd, Department of History and Philosophy of Science, 130 Goodbody Hall, Indiana University, Bloomington, IN 47405; e-mail: [email protected]; Richard Lewontin, Department of Organismic and Evolutionary Biology, Harvard University, 26 Oxford Street, Cambridge, MA 02138; Marcus Feldman, Department of Biological Sciences, Stanford University, Stanford, CA 94305; e-mail: [email protected]. (shrink)

The goal of this paper is to develop a systematic taxonomy of cognitive artifacts, i.e., human-made, physical objects that functionally contribute to performing a cognitive task. First, I identify the target domain by conceptualizing the category of cognitive artifacts as a functional kind: a kind of artifact that is defined purely by its function. Next, on the basis of their informational properties, I develop a set of related subcategories in which cognitive artifacts with similar properties can be grouped. In this (...) taxonomy, I distinguish between three taxa, those of family, genus, and species. The family includes all cognitive artifacts without further specifying their informational properties. Two genera are then distinguished: representational and non-representational (or ecological) cognitive artifacts. These genera are further divided into species. In case of representational artifacts, these species are iconic, indexical, or symbolic. In case of ecological artifacts, these species are spatial or structural. Within species, token artifacts are identified. The proposed taxonomy is an important first step towards a better understanding of the range and variety of cognitive artifacts and is a helpful point of departure, both for conceptualizing how different artifacts augment or impair cognitive performance and how they transform and are integrated into our cognitive system and practices. (shrink)

A framework is developed for understanding what is “taken for granted” both in philosophy and in life generally, which may serve to orient philosophical inquiry and make it more effective. The framework takes in language and its development, as well as mathematics, logic, and the empirical sphere with particular reference to the exigencies of life. It is evaluated through consideration of seven philosophical issues concerned with such topics as solipsism, sense data as the route to knowledge, the possible reduction of (...) geometry to logic, and the existence and status of human rights. Various dichotomies and the notion of continuity are evidently highly strategic. (shrink)

Contemporary discussion of biological teleology has been dominated by a complacent orthodoxy. Responsibility for this shortcoming rests primarily, I think, with those who ought to have been challenging dogma but have remained silent, leaving the orthodox to grow soft, if happily. In this silence, champions of orthodoxy have declared a signal victory, proclaiming the dominance of their view as one of philosophy’s historic successes. But this declaration is premature at best—this would be neither the first nor probably the last time (...) that a narrow school of philosophy has declared the resolution of age-old problems only to have those problems rise from the ashes of their better selves when a broader view is articulated. I propose to challenge orthodoxy by undermining its fundamental assumption and to enlist the help of others in articulating a formidable heterodox alternative to contemporary dogma concerning biological teleology, perhaps on the model I sketch below. (shrink)

This work is the transcript of a theological dialogue I had with ChatGPT that spanned a couple of days. I began it merely out of curiosity over how ChatGPT might respond to questions and challenges I posed. As it progressed, I became increasingly impressed with the nuance, depth, and relevance of its responses. The dialogue became, for me, something of a contemplative exercise. I still don’t know quite how to understand the ability of generative A.I. to respond with such (apparent) (...) understanding and even insight. -/- I’ve decided to post this dialogue, not only because of the puzzle it poses concerning A.I, but even more, because I believe that the theological conclusions ‘we’ arrived at have real merit. -/- In the end, the theological views expressed here echo those that I’ve expressed in other works of mine, but the expression of these views are enhanced by the way ChatGPT picks up on them, rephrases them, elaborates upon them, and often places them in the context of the classical theological tradition. -/- I might add that I have been an A.I. skeptic for some time now, concerned over the potential dangers of A.I. in general. But this dialogue, anyway, reveals its potential use as a vehicle for reflection, even profound reflection. -/- . (shrink)

This paper analyses the phenomenology and epistemology of chatbots such as ChatGPT and Bard. The computational architecture underpinning these chatbots are large language models (LLMs), which are generative artificial intelligence (AI) systems trained on a massive dataset of text extracted from the Web. We conceptualise these LLMs as multifunctional computational cognitive artifacts, used for various cognitive tasks such as translating, summarizing, answering questions, information-seeking, and much more. Phenomenologically, LLMs can be experienced as a “quasi-other”; when that happens, users anthropomorphise them. (...) For most users, current LLMs are black boxes, i.e., for the most part, they lack data transparency and algorithmic transparency. They can, however, be phenomenologically and informationally transparent, in which case there is an interactional flow. Anthropomorphising and interactional flow can, in some users, create an attitude of (unwarranted) trust towards the output LLMs generate. We conclude this paper by drawing on the epistemology of trust and testimony to examine the epistemic implications of these dimensions. Whilst LLMs generally generate accurate responses, we observe two epistemic pitfalls. Ideally, users should be able to match the level of trust that they place in LLMs to the degree that LLMs are trustworthy. However, both their data and algorithmic opacity and their phenomenological and informational transparency can make it difficult for users to calibrate their trust correctly. The effects of these limitations are twofold: users may adopt unwarranted attitudes of trust towards the outputs of LLMs (which is particularly problematic when LLMs hallucinate), and the trustworthiness of LLMs may be undermined. (shrink)

The purpose of this note is to present a strong form of the liar paradox. It is strong because the logical resources needed to generate the paradox are weak, in each of two senses. First, few expressive resources required: conjunction, negation, and identity. In particular, this form of the liar does not need to make any use of the conditional. Second, few inferential resources are required. These are: (i) conjunction introduction; (ii) substitution of identicals; and (iii) the inference: From ¬(p (...) ∧ p), infer ¬ p. It is, interestingly enough, also essential to the argument that the ‘strong’ form of the diagonal lemma be used: the one that delivers a term λ such that we can prove: λ = ¬ T(⌈λ⌉); rather than just a sentence Λ for which we can prove: Λ ≡ ¬T(⌈Λ⌉). The truth-theoretic principles used to generate the paradox are these: ¬(S ∧ T(⌈¬S⌉); and ¬(¬S ∧ ¬T(⌈¬S⌉). These are classically equivalent to the two directions of the T-scheme, but they are intuitively weaker. The lesson I would like to draw is: There can be no consistent solution to the Liar paradox that does not involve abandoning truth-theoretic principles that should be every bit as dear to our hearts as the T-scheme. So we shall have to learn to live with the Liar, one way or another. (shrink)

This paper argues that a popular account of intentions can be extended to beliefs. Beliefs are stable all-out states that allow for planning and coordination in a way that is tractable for cognitively limited creatures like human beings. Scepticism is expressed that there is really anything like credences as standardly understood.

So-called `disentangled' truth-theories are supposed to prevent assumptions about the truth of statements in the object-language from inadvertently strengthening the background syntax. In earlier work, I proved some limitative results in an attempt to show that the strategy works, but those results leave several questions unanswered. We address some of them here. We also discuss a subtlety that has so far been overlooked in discussions of these theories.

This is the second part of my theological dialogue with ChatGPT on the meaning of God. We explore the nature of God's agency, will, goodness, the problem of evil and suffering, the meaning of sin, and the meaning and nature of the redemptive act of Christ.

A contemplative prose-poem on the meaning of the Cross of Christ.

I discuss a puzzle that arises as an apparent tension between plausible theories of good guessing and intuitive constraints on rational inquiry. Clearly, our best guess at a question should reflect the likelihoods we assign to its possible answers. Your best guess is the answer you judge most likely. Additionally, it seems like a requirement of rational inquiry that our guesses be coherent. Thus, our best guess to a constituent (wh-) questions should cohere with our best guess to a polar (...) (yes/no) question whenever answers to the former entail answers to the latter. I argue that these requirements are in conflict and that a familiar form of contextualism doesn’t resolve the issue. The puzzle stands as a challenge to existing accounts of rational inquiry and question directed attitudes like guessing. (shrink)

All humans have an equal basic moral status. They possess the same fundamental rights, and the comparable interests of each person should count the same in calculations that determine social policy. Neither supposed racial differences, nor skin color, sex, sexual orientation, ethnicity, intelligence, nor any other differences among humans negate their fundamental equal worth and dignity. These platitudes are virtually universally affirmed. A white supremacist racist or an admirer of Adolf Hitler who denies them is rightly regarded as beyond the (...) pale of civilized dialogue. However, a very simple line of argument developed by Peter Singer challenges our understanding of these platitudes and forces us to rethink the basis and nature of the moral equality of all humans. What I call the “Singer Problem” arises if one accepts that the morally significant cognitive capacities that are relevant to the determination of the fundamental moral status of a being vary from individual to individual by degree. The problem is to specify a moral principle determining fundamental moral status that assigns a superior status to humans compared to other animals on the basis of the superior cognitive capacities of humans but also assigns all human persons an equal fundamental moral status regardless of their differing cognitive capacities. More broadly posed, the problem is to specify moral principles that yield intuitively satisfactory implications for the treatment of human individuals and other individual animals given that cognitive capacities differ across species and individuals. A search for a resolution of the Singer problem leads to disappointing results. (shrink)

This paper considers a now familiar argument that the ubiquity of context -dependence threatens the project of natural language semantics, at least as that project has usually been conceived: as concerning itself with `what is said' by an utterance of a given sentence. I argue in response that the `anti-semantic' argument equivocates at a crucial point and, therefore, that we need not choose between semantic minimalism, truth-conditional pragmatism, and the like. Rather, we must abandon the idea, familiar from Kaplan and (...) others, that utterances express propositions `relative to contexts' and replace it with the Strawonian idea that speakers express propositions by making utterances in contexts. The argument for this claim consists in a detailed investigation of the particular case of demonstratives, which I argue demand such a Strawsonian treatment. I then respond to several objections, the most important of which allege that the Strawsonian account somehow undermines the project of natural language semantics, or threatens the semantics -pragmatics distinction. Please note that the paper posted here is an extended version of what was published. (shrink)

What we value, like, endorse, want, and prefer changes over the course of our lives. Richard Pettigrew presents a theory of rational decision making for agents who recognise that their values will change over time and whose decisions will affect those future times.

Philosophers have been talking about brain states for almost 50 years and as of yet no one has articulated a theoretical account of what one is. In fact this issue has received almost no attention and cognitive scientists still use meaningless phrases like 'C-fiber firing' and 'neuronal activity' when theorizing about the relation of the mind to the brain. To date when theorists do discuss brain states they usually do so in the context of making some other argument with the (...) result being that any discussion of what brain states are has a distinct en passant flavor. In light of this it is a goal of mine to make brain states the center of attention by providing some general discussion of them. I briefly look at the argument of Bechtel and Mundale, as I think that they expose a common misconception philosophers had about brain states early on. I then turn to briefly examining Polger's argument, as I think he offers an intuitive account of what we expect brain states to be as well as a convincing argument against a common candidate for knowledge about brain states that is currently "on the scene." I then introduce a distinction between brain states and states of the brain: Particular brain states occur against background states of the brain. I argue that brain states are patterns of synchronous neural firing, which reflects the electrical face of the brain; states of the brain are the gating and modulating of neural activity and reflect the chemical face of the brain. (shrink)

It has been known for a few years that no more than Pi-1-1 comprehension is needed for the proof of "Frege's Theorem". One can at least imagine a view that would regard Pi-1-1 comprehension axioms as logical truths but deny that status to any that are more complex—a view that would, in particular, deny that full second-order logic deserves the name. Such a view would serve the purposes of neo-logicists. It is, in fact, no part of my view that, say, (...) Delta-3-1 comprehension axioms are not logical truths. What I am going to suggest, however, is that there is a special case to be made on behalf of Pi-1-1 comprehension. Making the case involves investigating extensions of first-order logic that do not rely upon the presence of second-order quantifiers. A formal system for so-called "ancestral logic" is developed, and it is then extended to yield what I call "Arché logic". (shrink)

In this paper I argue that a priori arguments fail to present any real problem for physicalism. They beg the question against physicalism in the sense that the argument will only seem compelling if one is already assuming that qualitative properties are nonphysical. To show this I will present the reverse-zombie and reverse-knowledge arguments. The only evidence against physicalism is a priori arguments, but there are also a priori arguments against dualism of exactly the same variety. Each of these parity (...) arguments has premises that are just as intuitively plausible, and it cannot be the case that both the traditional scenarios and the reverse-scenarios are all ideally conceivable. Given this one set must be merely prima facie conceivable and only empirical methods will tell us which is which. So, by the time a priori methodology will be of any use it will be too late. (shrink)

This paper discusses the question whether it is possible to explain the notion of a singular term without invoking the notion of an object or other ontological notions. The framework here is that of Michael Dummett's discussion in Frege: Philosophy of Language. I offer an emended version of Dummett's conditions, accepting but modifying some suggestions made by Bob Hale, and defend the emended conditions against some objections due to Crispin Wright. This paper dates from about 1989. It originally formed part (...) of a very early draft of what became my Ph.D. dissertation. I rediscovered it and began scanning it, when I had nothing better to do, in Fall 2001, making some minor editing changes along the way. Suffice it to say that it no longer represents my current views. I hope, however, that it remains of some small interest. (shrink)

We provide a philosophical reconstruction and analysis of the debate on the scientific status of cosmic inflation that has played out in recent years. In a series of critical papers, Ijjas et al. have questioned the scientificality of the current views on cosmic inflation. Proponents of cosmic inflation have in turn defended the scientific credentials of their approach. We argue that, while this defense, narrowly construed, is successful against Ijjas et al., the latter's reasoning does point to a significant epistemic (...) issue that arises with respect to inflation. A broadening of the concept of theory assessment is needed to address that issue in an adequate way. (shrink)

Consensus statement by UK teachers of medical ethics and law.

In this paper, we seek a reliabilist account of justified credence. Reliabilism about justified beliefs comes in two varieties: process reliabilism (Goldman, 1979, 2008) and indicator reliabilism (Alston, 1988, 2005). Existing accounts of reliabilism about justified credence comes in the same two varieties: Jeff Dunn (2015) proposes a version of process reliabilism, while Weng Hong Tang (2016) offers a version of indicator reliabilism. As we will see, both face the same objection. If they are right about what justification is, it (...) is mysterious why we care about justification, for neither of the accounts explains how justification is connected to anything of epistemic value. We will call this the Connection Problem. I begin by describing Dunn’s process reliabilism and Tang’s indicator reliabilism. I argue that, understood correctly, they are, in fact, extensionally equivalent. That is, Dunn and Tang reach the top of the same mountain, albeit by different routes. However, I argue that both face the Connection Problem. In response, I offer my own version of reliabilism, which is both process and indicator, and I argue that it solves that problem. Furthermore, I show that it is also extensionally equivalent to Dunn’s reliabilism and Tang’s. Thus, I reach the top of the same mountain as well. (shrink)

In a recent publication in this journal, Asle Kiran and Peter-Paul Verbeek (hereafter K&V) argue that extension theory and the notion of trust it implies are flawed. In this commentary, I defend extension theory against their critique. I first briefly introduce extension theory, then reconstruct K&V’s five arguments against extension theory and demonstrate that four of their five arguments are misplaced.

The complementary properties and functions of cognitive artifacts and other external resources are integrated into the human cognitive system to varying degrees. The goal of this paper is to develop some of the tools to conceptualize this complementary integration between agents and artifacts. It does so by proposing a multidimensional framework, including the dimensions of information flow, reliability, durability, trust, procedural transparency, informational transparency, individualization, and transformation. The proposed dimensions are all matters of degree and jointly they constitute a multidimensional (...) space in which situated cognitive systems can be located and have certain dimensional configurations. These dimensions provide a new perspective on the conditions for cognitive extension. They are, however, not meant to provide a set of necessary and sufficient conditions, but to provide a toolbox for investigating the degree and nature of the integration of agent and artifact into “new systemic wholes”. The higher a situated system scores on the proposed dimensions, the more functional integration occurs, and the more tightly coupled the system is. (shrink)

In this article, I outline various ways in which artifacts are interwoven with autobiographical memory systems and conceptualize what this implies for the self. I first sketch the narrative approach to the self, arguing that who we are as persons is essentially our life story, which, in turn, determines our present beliefs and desires, but also directs our future goals and actions. I then argue that our autobiographical memory is partly anchored in our embodied interactions with an ecology of artifacts (...) in our environment. Lifelogs, photos, videos, journals, diaries, souvenirs, jewelry, books, works of art, and many other meaningful objects trigger and sometimes constitute emotionally laden autobiographical memories. Autobiographical memory is thus distributed across embodied agents and various environmental structures. To defend this claim, I draw on and integrate distributed cognition theory and empirical research in human-technology interaction. Based on this, I conclude that the self is neither defined by psychological states realized by the brain nor by biological states realized by the organism, but should be seen as a distributed and relational construct. (shrink)

Can we find a phenomenological basis for the ethical 'ought'? This essay addresses this question through a reflection on Husserl's fifth Meditation. In the fifth Meditation Husserl endeavors to show the manner in which I constitute the other through an associative pairing of the other with my own subjectivity. This essay argues that this same associative pairing forces me to acknowledge the other as a person of intrinsic worth insofar as I recognize myself as one. Having acknowledged the intrinsic worth (...) of the other in this way, I cannot but acknowledge my obligation to treat the other as I would like to be treated. Thus, the ethical imperative, in the form of the Golden Rule, proves to be implicated in the very constitution of the other in his or her otherness. (shrink)

What are the possible varieties of cognition-artifact relations, and which dimensions are relevant for exploring these varieties? This question is answered in two steps. First, three levels of functional and informational integration between human agent and cognitive artifact are distinguished. These levels are based on the degree of interactivity and direction of information flow, and range from monocausal and bicausal relations to continuous reciprocal causation. In these levels there is a hierarchy of integrative processes in which there is an increasing (...) degree of hybridization. Therefore, from a functional and informational level of abstraction, it becomes increasingly difficult to distinguish between agent and artifact in this hierarchy. Second, a multidimensional matrix for exploring cognition-artifact relations is sketched. The dimensions in the matrix include reliability, durability, trust, procedural and representational transparency, individualization, bandwidth, speed of information flow, distribution of computation, and cognitive and artifactual transformation. Together, these dimensions constitute a multidimensional space in which particular cognition-artifact relations can be located. The higher a particular cognition-artifact relation scores on these dimensions, the more integration and hybridization occurs, and the more tightly coupled the overall system is. It is then better, for explanatory reasons, to see agent and artifact as one cognitive system with a distributed informational architecture. (shrink)

Emotional states of consciousness, or what are typically called emotional feelings, are traditionally viewed as being innately programed in subcortical areas of the brain, and are often treated as different from cognitive states of consciousness, such as those related to the perception of external stimuli. We argue that conscious experiences, regardless of their content, arise from one system in the brain. On this view, what differs in emotional and non-emotional states is the kind of inputs that are processed by a (...) general cortical network of cognition, a network essential for conscious experiences. Although subcortical circuits are not directly responsible for conscious feelings, they provide non-conscious inputs that coalesce with other kinds of neural signals in the cognitive assembly of conscious emotional experiences. In building the case for this proposal, we defend a modified version of what is known as the higher-order theory of consciousness. (shrink)

The chapter addresses the problem of the socio-ecological transformation of industrialized societies determined by the ideology of growth. It points out that the knowledge of the impossibility of sustainable growth on a planet with finite resources has been available at least since the 1960s. However, economic policies, as well as organizational principles and imperatives of public and private institutions, have so far been formulated regarding the growth imperative. However, the concepts of the Anthropocene and Planetary boundaries formulated within the framework (...) of Earth System Sciences already precisely confirm the devastation of the planetary system on a scale that threatens the survival of civilization in its current geographical scope and complexity. Socio-ecological transformation thus appears as a necessary prerequisite for preserving the environmental conditions for the existence of organized human society. The concept of de-growth provides a theoretical basis for establishing societal boundaries, i.e. the total rate of resource consumption and the amount of waste and emissions that a society can produce to prevent planetary boundaries from being exceeded. However, as long as public policies continue to be subordinated to the imperative of growth and fictions about unlimited resources or the infinite capacity of the planetary system to absorb all forms of pollution, all so-called green policies or transformations will remain just rhetorical exercises, but more or less sophisticated forms of greenwashing. (shrink)

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

The desirability of what actually occurs is often influenced by what could have been. Preferences based on such value dependencies between actual and counterfactual outcomes generate a class of problems for orthodox decision theory, the best-known perhaps being the so-called Allais Paradox. In this paper we solve these problems by extending Richard Jeffrey's decision theory to counterfactual prospects, using a multidimensional possible-world semantics for conditionals, and showing that preferences that are sensitive to counterfactual considerations can still be desirability maximising. (...) We end the paper by investigating the conditions necessary and sufficient for a desirability function to be an expected utility. It turns out that the additional conditions imply highly implausible epistemic principles. (shrink)

Orang-utans played a communication game in two studies testing their ability to produce and comprehend requestive pointing. While the ‘communicator’ could see but not obtain hidden food, the ‘donor’ could release the food to the communicator, but could not see its location for herself. They could coordinate successfully if the communicator pointed to the food, and if the donor comprehended his communicative goal and responded pro-socially. In Study 1, one orang-utan pointed regularly and accurately for peers. However, they responded only (...) rarely. In Study 2, a human experimenter played the communicator’s role in three conditions, testing the apes’ comprehension of points of different heights and different degrees of ostension. There was no effect of condition. However, across conditions one donor performed well individually, and as a group orang-utans’ comprehension performance tended towards significance. We explain this on the grounds that comprehension required inferences that they found difficult – but not impossible. The finding has valuable implications for our thinking about the development of pointing in phylogeny. (shrink)

Critics have often misunderstood the higher-order theory (HOT) of consciousness. Here we clarify its position on several issues, and distinguish it from other views such as the global The higher-order theory (HOT) of consciousness has often been misunderstood by critics. Here we clarify its position on several issues, and distinguish it from other views such as the global workspace theory (GWT) and early sensory models (e.g. first-order local recurrency theories). For example, HOT has been criticized for over-intellectualizing consciousness. We show (...) that while higher-order states are cognitively assembled, the requirements are actually considerably less than often presumed. In this sense HOT may be viewed as an intermediate position between GWT and early sensory views. Also, we clarify that most proponents of HOT do not stipulate consciousness as equivalent to metacognition or confidence. Further, compared to other existing theories, HOT can arguably account better for complex everyday experiences, such as of emotions and episodic memories. This makes HOT particularly useful as a framework for conceptualizing pathological mental states. (shrink)

Burke suggests that we should view society as a partnership between the past, the present, and the future. I defend this idea by outlining how we can understand the interests of the past and future people and the obligations that they have towards each other. I argue that we have forward-looking obligations to leave the world a decent place, and backward-looking obligations to respect the legacy of the past. The latter obligation requires an understanding of the role that traditions and (...) meta-traditions should (and should not) play in tying together societies—especially national societies—over time. (shrink)

The political philosophy originates from the reflections of crisis, risks and threats which society faces to. The author understands environmentalism as a tendency of current political philosophy which starts from the reflections of causes and possible effects of global environmental crisis as one of the most serious threats to the existential preconditions of current political system and global civilization at all. Considering the changes in social, technological and environmental starting conditions of the existence of economic-political system – that are consequences (...) of the transition from stable geologic-climate era of Holocene to unstable era of anthropocene – it is necessary to reconsider once more the basic premises, imperatives and conceptual frames of current economic-political system. The outlines of current economic-political system in philosophical frame were laid out by founders of modern political thinking while we can identify some of basic premises of environmentalism and also concepts relevant to the reflection of current threats and risks in some of their works. Author considers the concept of civil and human rights, the concept of natural state and the concept of social contract to be suitable for the reflection of the crisis of current economic-political system regarding environmentalism. Afterwards, the author formulates in what meanings are these concepts actual also for anthropocene. In conclusion, the author´s hypothesis is that the political philosophy of 21st century must reflect the environmental preconditions and limits of existence and forms of economic-political system and, at the same time, it must take into account that any economic and social activities have influence on the quality and sustainability of environment. (shrink)

The primary goal of this essay is to provide a comprehensive overview and analysis of the various relations between material artifacts and the embodied mind. A secondary goal of this essay is to identify some of the trends in the design and use of artifacts. First, based on their functional properties, I identify four categories of artifacts co-opted by the embodied mind, namely (1) embodied artifacts, (2) perceptual artifacts, (3) cognitive artifacts, and (4) affective artifacts. These categories can overlap and (...) so some artifacts are members of more than one category. I also identify some of the techniques (or skills) we use when interacting with artifacts. Identifying these categories of artifacts and techniques allows us to map the landscape of relations between embodied minds and the artifactual world. Second, having identified categories of artifacts and techniques, this essay then outlines some of the trends in the design and use of artifacts, focussing on neuroprosthetics, brain-computer interfaces, and personalisation algorithms nudging their users towards particular epistemic paths of information consumption. (shrink)

In an earlier paper, "Non-conceptual Content and the 'Space of Reasons'", I distinguished two forms of the view that perceptual content is non-conceptual, which I called the 'state view' and the 'content view'. On the latter, but not the former, perceptual states have a different kind of content than do cognitive states. Many have found it puzzling why anyone would want to make this claim and, indeed, what it might mean. This paper attempts to address these questions.

BACKGROUND Patients with chronic pain face significant barriers in finding clinicians to manage long-term opioid therapy (LTOT). For patients on LTOT, it is increasingly common to have them sign opioid treatment agreements (OTAs). OTAs enumerate the risks of opioids, as informed consent documents would, but also the requirements that patients must meet to receive LTOT. While there has been an ongoing scholarly discussion about the practical and ethical implications of OTA use in the abstract, little is known about how clinicians (...) use them and if OTAs themselves modify clinician prescribing practices. OBJECTIVE To determine how clinicians use OTAs and the potential impacts of OTAs on opioid prescribing. DESIGN We conducted qualitative analysis of four focus groups of clinicians from a large Midwestern academic medical center. Groups were organized according to self-identified prescribing patterns: two groups for clinicians who identified as prescribers of LTOT, and two who did not. PARTICIPANTS 17 clinicians from General Internal Medicine, Family Medicine, and Palliative Care were recruited using purposive, convenience sampling. APPROACH Discussions were recorded, transcribed, and analyzed for themes using reflexive thematic analysis by a multidisciplinary team. KEY RESULTS Our analysis identified three main themes: (1) OTAs did not influence clinicians’ decisions whether to use LTOT generally but did shape clinical decision-making for individual patients; (2) clinicians feel OTAs intensify the power they have over patients, though this was not uniformly judged as harmful; (3) there is a potential misalignment between the intended purposes of OTAs and their implementation. CONCLUSION This study reveals a complicated relationship between OTAs and access to pain management. While OTAs seem not to impact the clinicians’ decisions about whether to use LTOT generally, they do sometimes influence prescribing decisions for individual patients. Clinicians shared complex views about OTAs’ purposes, which shows the need for more clarity about how OTAs could be used to promote shared decision-making, joint accountability, informed consent, and patient education. (shrink)

Rescorla (Erkenntnis, 2020) has recently pointed out that the standard arguments for Bayesian Conditionalization assume that whenever I become certain of something, it is true. Most people would reject this assumption. In response, Rescorla offers an improved Dutch Book argument for Bayesian Conditionalization that does not make this assumption. My purpose in this paper is two-fold. First, I want to illuminate Rescorla’s new argument by giving a very general Dutch Book argument that applies to many cases of updating beyond those (...) covered by Conditionalization, and then showing how Rescorla’s version follows as a special case of that. Second, I want to show how to generalise R. A. Briggs and Richard Pettigrew’s Accuracy Dominance argument to avoid the assumption that Rescorla has identified (Briggs and Pettigrew in Noûs, 2018). In both cases, these arguments proceed by first establishing a very general reflection principle. (shrink)

Conservative assumptions in medical ethics risk immense harms during a pandemic. Public health institutions and public discourse alike have repeatedly privileged inaction over aggressive medical interventions to address the pandemic, perversely increasing population-wide risks while claiming to be guided by ‘caution’. This puzzling disconnect between rhetoric and reality is suggestive of an underlying philosophical confusion. In this paper, I argue that we have been misled by status quo bias—exaggerating the moral significance of the risks inherent in medical interventions, while systematically (...) neglecting the risks inherent in the status quo prospect of an out-of-control pandemic. By coming to appreciate the possibility and significance of status quo risk, we will be better prepared to respond appropriately when the next pandemic strikes. (shrink)

A personal reflection on the meaning of worship and the 'worthiness' of God.